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Mechanistic tool in preclinical work: Used to explore lipid and glucose metabolism pathways in controlled models of energy balance

Funding: The present study was partly supported by the Samuel Rahbar Diabetes and Drug Discovery Endowment, Arthur Riggs Diabetes & Metabolism Research Institute and innovation grant from the Wanek Family Project for Type 1 Diabetes at City of Hope

Research has documented their role in promoting blood vessel genesis, reducing fibrotic scarring, and supporting recovery from neurological injury

10.1038/ncomms12015 211 JarrettJ

Signs and symptoms often associated with B12 deficiency include: Fatigue Lethargy Headaches Mouth ulcers Vision changes Brain fog Low energy Irregular sleep patterns Slow metabolism