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These values should be interpreted against the absence of internationally harmonized regulatory limits for HCAs in food, a regulatory gap reflecting ongoing scientific debate about dose-response relationships at typical dietary exposure levels

[DOI] [PubMed] [Google Scholar] 521.Daz-de-Cerio E., Verardo V., Gmez-Caravaca A.M., Fernndez-Gutirrez A., Segura-Carretero A

This suggests that sleep restriction used in clinical practice to treat insomnia can increased SWA and subjective sleep quality in individuals with insomnia, especially those with deficits in SWA as shown in the SSDD and NSDD subtypes