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In high-fat diet-induced models of obesity and MASLD, SRT1720 upregulates PGC-1 and PPAR expression, promoting fatty acid -oxidation and reducing hepatic triglyceride levels

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A controlled blood volume removal was conducted until the death or stabilized low blood pressure (30-35 mm Hg)

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In addition, OmTGF- negatively correlated with cholesterol and LDL whereas OmTNF positively correlated with glucose and HDL (Additional file 1: Table 6)

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