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In SKOV-3 cells, the AGN/RSV NPs groups antiproliferation efficiency was noticeably greater than that of the AGN extract, AGN NPs, and AGN NPs + RSV groups

A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily

[DOI] [PubMed] [Google Scholar] 62.Hosoda H, Kojima M, Mizushima T, Shimizu S, Kangawa K

The primary pathological hallmark of PD is the progressive loss of dopaminergic neurons in the substantia nigra pars compacta

Importantly, no serious complicationssuch as endometriosis, ovarian malignancies, or autoimmune diseaseswere reported, suggesting that autologous MenSC transplantation represents a safe and promising approach for improving reproductive outcomes in women with ovarian insufficiency (Table 1)