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Structure assignment revealed several key metabolic sites and diverse biotransformation pathways, including ester hydrolysis, aldehyde reduction, aldehyde oxidation, hydroxylation (monohydroxylation and dihydroxylation), glucuronidation, and the cross-combination of these pathways

One other critical target of PKA phosphorylation is the transcription factor CREB (cAMP response element binding-protein)

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Oscillations in the RLS and a thermal arrest in the cooling section of the thermogram confirmed that the sample had melted and re-solidified