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The phosphorylation reactions of the MAPK cascade, activated by growth factors (e.g., IGF-1 and IGF-2), culminate in the nuclear translocation of extracellular signal-regulated kinases (ERK) and the activation of transcription factors that control key cell cycle events

doi: 10.7554/eLife.71846 85 O'ReillyE

Therapeutic targeting of ferroptosis in ARDS includes the use of antioxidants, GPX4 activators, iron chelators, and inhibitors of lipid peroxidation

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Abstract Natural substances originating from plants have long been used to treat neurodegenerative disorders (NDs)