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Autophagy flux was increased in high altitude hypoxic environment, as evidenced by an increase in the ratio of microtubule-associated protein 1 light chain type 3 II/I (LC3-II/I) and an increase in the expression of LC3-II (Masschelein et al., 2014)
Scores of 2 or more were indicative of skin benefits assessed as visibly significant by both the investigator and the subjects

Journal of Neurochemistry 64, 19651972 [DOI] [PubMed] [Google Scholar] Brown G.C

In other studies of liver fibrosis, elevated serum copper was due to the increased absorption of intestinal copper to the circulation and increased release of copper from damaged cells 29,30