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4 Clinical translation to target ferroptosis and immune combination strategies 4.1 Therapeutic potential and immunomodulatory effects of ferroptosis inducers Preclinical studies have suggested that ferroptosis inducers, such as erastin, RSL3, and FIN56, have significant antitumor activity in GBM

Tyrosinase inhibitors stop the conversion of tyrosine into melanin, which is the pigment that gives skin its color

The oral bioavailability of peptides is a subject of ongoing scientific debate

The Lancet 405(10476):354-356, 2025

Notably, the UniProtKB entry for C16orf87 (UniProtKB Q6PH81) annotates a putative coiled-coil region between residues 104132
