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Hypothyroidism may functionally have an effect on the development of the adrenal gland cortex, its hormone production, and the adrenal medulla, further exacerbating systemic metabolic dysregulation (Patyra et al

To further estimate the effect of ER stress activation during OGD, cells were pretreated with 4-phenylbutyric acid (4-PBA) (1 mM) for 1 h
This can result in a slowed metabolic rate and increased fat storage

Tateishi, Role of membrane transport in metabolism and function of glutathione in mammals

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