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doi: 10.1042/bj2260545
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A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinsons disease (the ADAGIO study): rationale, design, and baseline characteristics
Sanacora et al
showed that ROS produced by CYP2E1 induces an increase in Nrf2 expression, which promotes the upregulation of GSH-related genes as a compensatory mechanism [153]
