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Insulin, insulin-like growth factors and neoplasia

Further study of this clinically relevant route of administration for mitochondria-targeting compounds is warranted in TBI animal models to optimize this route and fully understand dosing, therapeutic window and safety issues related to the route

If significant fibrosis is confirmed, patients should be referred to a specialist to perform liver biopsy and confirm the diagnosis histologically ( Chronic inflammation is the driving force for the onset and progression of fibrosis in NASH ( 4