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Redox regulation of calcium ion channels: chemical and physiological aspects

NAC readily crosses the blood-brain barrier providing a cysteine substrate for GSH synthesis in the brain, in addition to acting directly as a scavenger of ROS (40)

Furthermore, pharmacological inhibition of PHGDH by NCT-503 enhanced sensitivity to bortezomib, and reduced the intracellular redox capacity of the multiple myeloma (MM) cells [142]

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Tumor tissues derived from the cecum and liver were mechanically dissociated and enzymatically digested at 37 C in a rotating incubator (250 rpm) for 1 h