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Efficacy of Curcumin and Piperine as Antioxidant Adjuvant to Intralesional Dexamethasone Injection for Management of Oral Submucous Fibrosis: A Clinical Trial

Mechanistically, the addition of negatively charged acetyl groups to specific lysine residues in histones could reduce the electrostatic affinity between histones and DNA, disrupting their interaction and leading to chromatin relaxation, thereby activating gene transcription

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According to the number and location of the catalytic cysteines, Prxs are divided into three classes: the typical 2-Cys, the atypical 2-Cys and the 1-Cys [46]