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Individuals with Gastrointestinal Disorders: Such as Crohns disease, celiac disease, atrophic gastritis, or those who have had gastric bypass surgery or other stomach/intestinal resections, which can interfere with B12 absorption

Belichenko et al., Since Rett syndrome manifests itself in early postnatal life when experience shapes neuronal circuit wiring, and since Mecp2 is activity-dependently regulated (Cohen et al., 2011), it is hypothesized that Mecp2 might mediate experience-dependent processes of synapse development

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Germ-free (GF) mice were kindly provided by M