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Referring to the anti-oxidant activity by H 2 S donors exerted on neurons, studies have found that H 2 S could increase the GSH concentration in neurons by enhancing the transporter of cysteine, cysteine/glutamate antiporter and -glutamyl cysteine synthetase (-GCS) 73,74

In parallel, conditionally essential nutrients were defined as those that may be synthesised in adequate amounts endogenously but could become rate-limiting under clinical conditions of stress whether from anabolic processes (e.g

Mitochondrial dysfunction plays a key role in the development of neurodegenerative diseases in diabetes

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