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Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome

Nature 367: 614621 Kyle DJ (1987) The biochemical basis for photoinhibition of Photosystem II

However, when the cell detects an apoptotic stimulus, such as DNA damage or metabolic stress, the intrinsic apoptotic pathway is triggered and mitochondrial cytochrome c is released into the cytosol (Kroemer et al., 2007)

Hinkel J, Schmitt J, Wurm M, et al

While the impact of cigarette smoking on the redox balance of several tissues has been extensively studied, its specific role in triggering oxidative injury in erythrocytes has only recently gained attention