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Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart. Mechanisms of ageing and development 133.2-3 (2012): 99-106

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It took me about 3 minutes to find this reference: Phosphotransferase systems involved in microbial processing of carbohydrates also were found to be over expressed in the intestines of obese people, notably from Prevotellaceae I am not saying that carbs increase Prevotella activity or that Prevotella causes heart attacks