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According to the leaky gut theory, these alterations in gut microbiota may be related to inadequate perfusion to the viscera due to cardiac congestion or impaired ejection capacity in patients with HF, and ischemic edema in the intestine caused by ischemia, which might increase the permeability of the intestinal epithelium (Sandek et al., 2007), thus allowing intestinal macrobiotic and bacterial metabolites to gain access to the circulatory system through the compromised barrier

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5.3 Apoptosis Apoptosis may be thought of as a sort of programmed cell death (202)

The Scottish and Finnish groups [23, 24] many years ago demonstrated the relationship between large triglyceride-rich VLDL and small dense LDL: the larger the VLDL, the smaller and denser the LDL