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Antioxidant Defense Increases superoxide dismutase (SOD) production one of the body's most important antioxidant enzymes

In contrast, whereas PPAR mRNA expression gradually increased with the aggravation of liver injury and rose in parallel with the increase in hepatic steatosis score, it was speculated that PPAR might promote the progression of steatosis[145]

2008;101(10):S43S49

Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose

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