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LL6, the most promising novel small molecule kinase inhibitor obtained, induced apoptosis and suppressed the colony-forming capacities of various drug-resistant NSCLC cell lines, suppressed NSCLC cell migration, suppressed NSCLC xenograft tumor growth and Lewis lung carcinoma allograft tumor metastasis in mice, and markedly reduced the number and burden of lung tumors in KrasG12D/+ transgenic mice, with low toxicity (54)

This system allows for the delivery of smaller volumes, resulting in stable plasma levels of LC without invasive procedures in patients experiencing motor fluctuations due to PD

Development of Nanozyme Based Sensors as Diagnostic Tools in Clinic Applications: A Review. Journal of Materials Chemistry B 11: 67626781

This highlights the need for further research to better understand ZEN metabolism and excretion in humans