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Curcumin-inducible HIF-1 degradation has been shown to impede the process of invasive metastasis in colorectal cancer cells by impeding glutamine catabolism through the inhibition of GLS1 and the suppression of EMT [66]

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GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer

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