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The antioxidant status in a horse plays an important role6 and dietary supplementation with natural antioxidants will enhance the horses antioxidant status, and minimise the risk of muscle injuries caused by oxidative stress

Jackson, P

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Mongioi L, Calogero AE, Vicari E, Condorelli RA, Russo GI, Privitera S, et al

CB1 and CB2 receptors are located both on neurons and glial cells and are considered the main circuit breakers, as activation of pre-synaptic CB1 (and possibly CB2) receptors inhibits the release of the major neurotransmitters glutamate (excitatory) and GABA (inhibitory) (Katona and Freund, 2008)