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In this population, 5 mg per day of folic acid significantly decreased homocysteine levels, to a degree believed to lower the risk of cardiovascular disease, and improved glycemic control (Sudchada 2012)

doi: 10.1093/jnci/95.3.237, PMID: [DOI] [PubMed] [Google Scholar] 269.Yuan S, Mason AM, Carter P, Vithayathil M, Kar S, Burgess S, et al

Additionally, the participants were in the preparatory phase for upcoming competitions, which made them an ideal sample for assessing the effects of supplementation on performance in an elite athletic population

Zuo D, Sun F, Cui J, Liu Y, Liu Z, Zhou X, Li Z, Wu Y

Orphenadrine (100 mg twice daily), an anticholinergic, significantly reduced cramp frequency, severity, and duration, as supported by a placebo-controlled trial with minimal side effects
