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IGF-1 has specific and stimulatory effects on granulosa cells, and it was reported to increase the expression of steroidogenic enzymes CYP11A1, 3-hroxysteroid dehydrogenase (3HSD), CYP19A1, along with IGF-1R, and FSHR gene expression (70)

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doi: 10.1007/s11154-018-9467-y 104 ViriliC.StramazzoI.BagagliniM

Liver transplantation for NASH-related hepatocellular carcinoma versus non-NASH etiologies of hepatocellular carcinoma
