glutathione-dependent detoxification pathway Glutathione Metabolism of the Brain—The Role of Astrocytes Glutathione-Mediated Conjugation of Anticancer Drugs:

When methylation is impaired and homocysteine starts to accumulate, the transsulfuration pathway takes the excess homocysteine and converts it through cystathionine to cysteine which your body then uses to make glutathione, your primary intracellular antioxidant [7, 13]

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Arch Pediatr Adolesc Med 161:35661, PMID: 17404132 Rezaei Z, Saadat I, Saadat M (2012) Association between three genetic polymorphisms of glutathione S -transferase Z1 (GSTZ1) and susceptibility to bipolar disorder

We began with the steady state for S = 1.8, but changed the value of S to 1.3 at t = 0, where the steady state of GSH is 6,842 M