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D.PatriA

Xiong H, Ou Y, Xu Y, Huang Q, Pang J, Lai L, Zheng Y

Copper(II)-glycyl-L-histidyl-L-lysine MOLECULAR FORMULA C 28 H 46 CuN 12 O 8 MOLECULAR WEIGHT 742.3 g/mol STRUCTURE Linear tripeptide PEPTIDE SEQUENCE Gly-His-Lys CHEMICAL STRUCTURE CAS Number: 300801-03-0 Molecular Formula : C 28 H 46 CuN 12 O 8 Source: PubChem Mechanism of Action GHK-Cu acts primarily by delivering bioavailable copper(II) to tissues and cells and modulating a range of biological pathways associated with repair and regeneration

The use of ACE inhibitors and ARBs with Alzheimers patients suggests an involvement by the brain RAS in this dysfunction

It has been demonstrated that the chelation of Cu 2+ and Fe 3+ by DHLA in the brain reduces free radical damage and may exert a protective action in the pathobiology of Alzheimers disease [17]