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(b) Simulation results of glutathione (GSH) concentration from integrative C1 metabolism model

In the CNS of both EAE mice and multiple sclerosis (MS) patients, there is a significant downregulation of CD320

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Although clinical and laboratory improvement can be seen with steroids, hepatic sarcoid can eventually progress to cause portal hypertension, bile duct depletion, and fibrotic changes, at which point steroids are unlikely to be of benefit
