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A Balanced Act of Mitochondrial Biogenesis and Mitophagy Mitochondrial function is multifaceted in response to cellular energy homeostasis and metabolism, including calcium homeostasis, amino acid metabolism, pyridine synthesis, cellular replication, apoptosis, reactive oxygen species (ROS) production, and senescence (Spinelli and Haigis, 2018)

MDA is a product of lipid peroxidation and an indicator of oxidative stress, while GSH is a vital antioxidant that plays a crucial role in cellular defense mechanisms

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