glutathione peroxidase 4 motor neuron JCI Small molecule selenium-based glutathione peroxidase
Description
Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3beta inhibition due to intracellular delivery of copper

note: This nucleophilicity is enhanced when cysteine gets deprotonated (loses an H) to give you an -S

Gently swirl the vial until the powder dissolves completely, usually 1 to 2 minutes

doi: 10.1002/mnfr.200900197

PGC1 is a key regulator of erastin-induced mitochondrial dysfunction during ferroptotic cell death
