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Drug delivery to the brain: recent advances and unmet challenges

493 In terms of chemotherapy sensitization, lactate has been found to confer chemoresistance by increasing the expression of multidrug resistance-associated protein 1 (MRP1, encoded by ATP-binding cassette sub-family C member 1 (ABCC1)), which induces drug efflux from cells

Tesseur I, Nguyen A, Chang B, Li L, Woodling NS, Wyss-Coray T, et al

In brief, mice were aneasthetized with xylazine/ketamine and shaved at their front

By reducing oxidative stress in skin tissues and interfering with melanin production (the process that gives skin its pigment), glutathione is thought to help brighten the complexion and address issues like dark spots or uneven tone
