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224 The inefficacy of CAR-T cell therapy can be attributed to multiple factors, among which T cell senescence and exhaustion play pivotal inhibitory roles

Therefore, rats received resveratrol 4 h after the beginning of the dark phase, which is supposed to overlap with Per2 and melatonin peaks

Nevertheless, the efficacy and safety of these strategies require further in-depth validation, and their clinical translation potential remains to be clarified
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Clin Inertv Aging (2007) 2:21936
