does nac convert to glutathione biosynthetic scheme. N-acetyl-L-cysteine (NAC) can supply Vitamin D, Glutathione, and NAC:

Yes, it circulates throughout the body rather than acting only at the injection site

doi: 10.3233/JAD-142223

Streu, C

The results of this study demonstrate that the fixed combination of ALA and GLA, in particular, in the early stages of the disease, represents a useful tool for managing symptoms and improving the course of CTS

In an observational study that included data from 193,072 atrial fibrillation patients treated with DOACs (dabigatran, rivaroxaban, apixaban, and edoxaban), the various DOACs were associated with similar benefits, but apixaban was correlated with the lowest and dabigatran with the second-lowest risks of major and clinically relevant non-major bleeding events