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While these results are highly encouraging, robust, large-scale human clinical trials are still needed to validate these effects and establish a definitive therapeutic profile in humans

The second controversial disease is Keshan disease

Additionally, Starobova et al

While rosacea is a chronic and incurable skin condition, advancements in medical and aesthetic treatments have made symptom management more effective

Some drawbacks of current ND treatment strategies, which primarily manage symptoms rather than address the underlying causes, include poor bloodbrain barrier permeability, drug resistance, adverse side effects, and inadequate drug absorption