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Content is updated for FY2026 ICD-10-CM (effective October 1, 2025)
Increased fetal resorption and other adverse effects on the fetus in rats at 7.3 to 11 times the MRHD and increase in congenital anomalies in rabbits at 7.3 to 22 times the MRHD on a mg/m 2 basis were observed
However, using antiscalants represents a more modern approach with several advantages over these traditional methods
