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Methods Materials Diamide, dithiothreitol (DTT), ethylenediaminetetraacetic acid (EDTA), GSH, GSSG, and yeast GR were from Sigma-Aldrich, l-cysteine was from Carl Roth, isopropyl--d-1-thiogalactopyranoside was from Serva, methyl ether poly(ethylene glycol) 24 maleimide (mmPEG) was from Iris Biotech, and NADPH was from Gerbu

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Animal models of myocardial infarction show that TB-500 administration improves left ventricular function, reduces infarct size and cardiomyocyte death during ischemic events, and enhances cardiac microvascular density to improve tissue perfusion