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The current therapeutic approach primarily focuses on symptom and heart rate management via rate and/or rhythm control, in addition to stroke prevention with the implementation of anticoagulation or mechanical exclusion of the left atrial appendage

doi: 10.1034/j.1600-0625.2002.110502.x

Regarding clinical drugs targeting microtubules, the classical example is paclitaxel, although its insolubility and drug resistance are a major challenge