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Description
Importantly, in our comparative analyses, phenformin strongly outcompeted metformin in terms of its antiviral activity which was ~300 fold higher against SARS-CoV-2 (IC 50 of ~1.5 M for phenformin vs ~450 M for metformin)
Indirect mechanisms have also been proposed, particularly in the context of androgen deficiency
The severity and patterns of these biochemical and molecular changes will be investigated and discussed 12 and 24 h after exposure to the stressors
All studies cited below are the work of their respective authors and institutions
doi: 10.1038/s41598-023-50600-8
