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Khorrami et al., 2017)
5-alpha reductase is the enzyme our bodies use to convert free testosterone into DHT
A healthcare professional can administer injectable therapies, or a person can do this at home
Yet another compound, Honokiol (HKL), has been shown to protect against doxorubicin-induced cardiotoxicity by activating SIRT3, which helps reduce ROS production, prevent mitochondrial fragmentation, and promote mitochondrial fusion 187
SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
