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Thus, coexisting acne and PIH were improving at an early time point of 4 weeks and continued to improve until week 16.23 At the end of the trial period, erythema and dryness were no longer reported, neither were serious AEs, highlighting the good tolerability in this population.23 Combination therapies By targeting multiple pathogenic processes underlying acne pathogenesis, combination therapies may have synergistic effects that better treat acne and PIH compared to monotherapy with any agent

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