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Next, the cell medium was replaced, and 100 L of different doses of AP probe-net (final concentration: 100, 75, 50, 25, 12.5, 6.25, 3.12 and 1.56 M) were added and incubated for another 24 h and 48 h, respectively

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Dynamic exclusion was set to 10 ppm for 60 s

Studies measured sleep onset and maintenance at Month 1 (sleep labs) and Month 6 (patient diaries)

The safest interpretation is that without explicit Category 1 placement, compounding carries significant regulatory uncertainty
