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Similar studies have also found that PRNP, a ferroptosis-related gene, is significantly associated with cancer stage, main treatment outcome, and age of OC patients by mining differential genes (DEGs) of OC through public datasets

To test the effect of Sp in paraquat-induced oxidative stress model, seven days old wild type flies, constitutively expressing mitochondrial (mt)-roGFP, were exposed to 10 mM paraquat for 24 h and then co-treated with 2.5 mM Sp for 24 h, prior to roGFP fluorescence estimation

NRF2-mediates HO-1 expression and ferroptosis resistance in KRAS mutant colorectal cancer cells, whereas combined cetuximab with RSL3 increases KEAP1 expression leading to inhibition of NRF2/HO-1 pathway [35]

Mass spectrometry can be used to accurately identify and quantify target proteins [43]

Dna damage following combination of radiation with the bioreductive drug aq4n: possible selective toxicity to oxic and hypoxic tumour cells