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So it would be advantageous to explore the possibilities of novel multi-target therapy, aimed to affect different disease-related mechanisms, resulting in additive or synergic therapeutic responses [7]
doi: 10.1007/s10637-012-9849-z

Lutein and beta-carotene have a treatment potential due to their antioxidant activity

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Metformin, rosiglitazone and recombinant human growth hormone have been used with variable efficacy
