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However, certain circumstances warrant medical review and potential investigation
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Appendix C
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Following the encouraging results as single agent, daratumumab was evaluated in combination with immune checkpoint inhibitors, immunomodulatory drugs and proteasome inhibitors (Fig
[10] [12] High-dose ascorbic acid may diminish the therapeutic effects of certain chemotherapeutic agents, such as bortezomib, due to its antioxidant properties
