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Description
Essar, D

Effects on the Endocrine System Opioids inhibit the secretion of adrenocorticotropic hormone (ACTH), cortisol, and luteinizing hormone (LH) in humans (see ADVERSE REACTIONS)

This pathway has been shown to contribute to synaptic dysfunction, neuroinflammation and glutamate dysregulation 60

without these methylation reactions, normal cell functions would not be possible

Paul and Snyder, 2012)
