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Patients with a history of intestinal surgery, strictures, or blind loops may have bacterial overgrowth that can compete for dietary vitamin B 12 in the small bowel, as can infestation with tapeworms or other intestinal parasites

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Post-mortem studies also find differences between treated and untreated patients with schizophrenia, showing a positive correlation between the density of GAD and antipsychotic dose and higher expression levels of GAD67 and GABA-A protein subunits in antipsychotic-treated patients relative to unmedicated patients [49]

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