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Description
The sequence begins with progesterone, which is converted to 17-hydroxyprogesterone by CYP17A1, then to 11-deoxycortisol by CYP21A2, and finally to cortisol by CYP11B1

It changes the measurement, not the dose
Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line

pmid:24845174 55

These warrant individual discussion since it is their features that may prompt referral for biopsy to exclude malignancy