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Nevertheless, since binding was observed, these results suggest that it is possible to adapt the selection conditions to identify more specific aptamers, for example by including more stringent conditions such as increased salt concentration (see BLI data in Supplementary Fig

CaCl 2 2.5, pH = 7.4, 37C, constantly aerated by gas mixture (95% O 2 and 5% CO 2 )

For the EGFP reporter-based system, the plasmid was introduced into BL21(DE3) E

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