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According to different experimental data, the misfolded/ unfolded protein emergence causes ER stress, which aids in the death of neurons or apoptosis [266,267,268]

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While these effects are generally transient, any severe or persistent reactionssuch as significant pain, allergic reactions, or signs of fluid retentionshould be documented and addressed according to laboratory protocols

[DOI] [PMC free article] [PubMed] [Google Scholar] Kumar D

The American Autoimmune Related Diseases Association (AARDA) estimates that about 20 million Americans have one or more forms of peripheral neuropathy