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The Functional Medicine View of Rosacea Functional medicine recognizes rosacea as a condition involving multiple interconnected systems: Gut microbiome Immune system regulation Nervous system activation Histamine signaling Skin barrier integrity Inflammatory cytokines Instead of viewing rosacea only through a dermatologic lens, functional medicine evaluates why the inflammatory response has become dysregulated

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Pretreatment with a Src inhibitor abolished these effects in HUVEC culture, placing Src upstream of the caveolin-1-eNOS step in the proposed cascade

Contracture occurred whether rats were awake/anesthetized and persisted after sacrifice