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Epilepsy phenotypes associated with COQ8A mutations include focal seizures, generalized tonicclonic seizures, myoclonic seizures, absence seizures, persistent partial epilepsy, and status epilepticus (129132)

May improve cholesterol Cacao has been reported to show varying degrees of improvement on LDL (low density lipoprotein) and total cholesterol

Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance

Consequently, the ratio between reduced (GSH) and oxidized (GSSG) forms of glutathione can serve as an indicator of the cellular redox state [138]

Drug treatment and indirect immunofluorescence microscopy Exponentially growing yeast cells were treated with oxidative agents 4NQO (5 g ml 1 ), menadione (0.5 mM), paraquat (1 mM) or H 2 O 2 (0.4 mM) for 1 h, or with DNA-damaging agent HU (100 mM) for 3 h, MMS (0.02%) for 3 h, zeocin (100 g ml 1 ) for 1 h or CPT (20 M) for 1 h